Eleanor “Nell” Vance (Lili Taylor) has cared for her invalid mother for 11 years. After her mother dies, her sister Jane (Virginia Madsen) and Jane's boyfriend Lou (Tom Irwin) evict her. Nell receives a phone call about an insomnia study, directed by Dr. David Marrow (Liam Neeson) at Hill House, a secluded manor in the Berkshires of western Massachusetts, and applies for it. At the house, she meets Mr. and Mrs. Dudley (Bruce Dern, Marian Seldes), a strange pair of caretakers. Two other participants arrive, Luke Sanderson (Owen Wilson), and Theodora (Catherine Zeta-Jones), along with Dr. Marrow and his two research assistants. Unknown to the participants, Dr. Marrow’s true purpose is to study the psychological response to fear, intending to expose his subjects to increasing amounts of terror. Each night, the caretakers chain the gate outside Hill House, preventing anyone from getting in or out until morning. During their first night, Dr. Marrow relates the story of Hill House. The house was built by Hugh Crain (Charles Gunning)—a 19th-century textile tycoon.